Title:
ベンゾピランおよびベンツオキセピン、それらを含む医薬組成物および製造方法
Document Type and Number:
Japanese Patent JP4607331
Kind Code:
B2
Abstract:
The present invention relates to benzopyrans and benzoxepines of formula (I), wherein X, A, R1, R2 and (R)p have the meanings as given in claim 1, which can be used in the treatment of dislipidaemias, atherosclerosis and diabetes, to pharmaceutical compositions comprising them and to processes allowing the preparation of these compounds.
Inventors:
Brunet, Michelle
Zeile, Jean, Jacque
Bertron, Jean, Jack
Contar, Francis
AUGEL, J
Guerrier, Daniel
Zeile, Jean, Jacque
Bertron, Jean, Jack
Contar, Francis
AUGEL, J
Guerrier, Daniel
Application Number:
JP2000591024A
Publication Date:
January 05, 2011
Filing Date:
December 20, 1999
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D311/58; A61K31/335; C07D335/06; A61K31/352; A61K31/38; A61K31/382; A61P3/10; A61P9/00; A61P9/10; C07D311/06; C07D311/96; C07D313/08; C07D313/10; C07D337/08
Domestic Patent References:
| JP2262563A | ||||
| JP3083979A | ||||
| JP10511948A | ||||
| JP6211829A |
Other References:
SATOH, Y., et al.,Bioorg. Med. Chem. Lett.,4(4),pp.549-552 (1994)
SEKHAR, B.C., et al.,Sulfur Lett.,10(3+4),pp.149-160 (1989)
SATOH, Y., et al.,J. Med. Chem.,36(23),pp.3580-3594 (1993)
RENE, L., e al.,Eur. J. Med. Chem.,10(1),pp.72-78 (1975)
BROWN, P.E., et al.,J. Chem. Res.(S),p.208 (1988)
FATOME, M., et al.,Eur. J. Med. Chem.,11(1),pp.81-82 (1976)
FONTAINE, G.,Ann. Chim.,3(3),pp.179-191 (1968)
SEKHAR, B.C., et al.,Sulfur Lett.,10(3+4),pp.149-160 (1989)
SATOH, Y., et al.,J. Med. Chem.,36(23),pp.3580-3594 (1993)
RENE, L., e al.,Eur. J. Med. Chem.,10(1),pp.72-78 (1975)
BROWN, P.E., et al.,J. Chem. Res.(S),p.208 (1988)
FATOME, M., et al.,Eur. J. Med. Chem.,11(1),pp.81-82 (1976)
FONTAINE, G.,Ann. Chim.,3(3),pp.179-191 (1968)
Attorney, Agent or Firm:
Akio Miyazaki
Katsuhiro Ito
Ishibashi Masayuki
Katsuhiro Ito
Ishibashi Masayuki