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Title:
BENZOXAZEPINE COMPOUND
Document Type and Number:
Japanese Patent JP2003064063
Kind Code:
A
Abstract:

To provide a compound which has lowering activity of cholesterol and triglyceride-reducing activity and is useful for preventing or treating hyperlipemia.

The compound represented by formula [I] [R1 is 3- carboxypropyl, 1-carboxyethyl, or a 3 to 6C linear alkyl-sulfonyl, a (carboxy-5 to 7C cycloalkyl)-1 to 3C alkyl, a (carboxyfuryl)-alkyl, carboxy-6 to 10C aryl, a (carboxy-2 or 3C alkyl)-6 to 10C aryl or a (carboxy-1 to 3C alkyl)-7 to 14C aralkyl, which may have substituents, respectively; R2 is an alkanoyloxy and/or an optionally hydroxylated 3 to 6C alkyl; R3 is a lower alkyl; W is a halogen atom, (provided that R2 is a 3 to 6C alkyl which has an alkanoyloxy and/or hydroxy, when R1 is 4-carboxycyclohexylmethyl or carboxyphenyl)] or its salt.


Inventors:
KORI MASAKI
MIKI TAKASHI
NISHIMOTO MASAYUKI
TOZAWA RYUICHI
Application Number:
JP2002233086A
Publication Date:
March 05, 2003
Filing Date:
June 22, 2001
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
C07D267/14; A61K31/553; A61P3/00; A61P3/06; A61P43/00; C07D413/12; C07D417/12; (IPC1-7): C07D267/14; A61K31/553; A61P3/00; A61P3/06; A61P43/00; C07D413/12; C07D417/12
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)