Title:
ベンジルアミノピリジルシクロプロパンカルボン酸、その医薬組成物および使用
Document Type and Number:
Japanese Patent JP7050797
Kind Code:
B2
Abstract:
wherein the groups R, R1, R2, R3, m and n are defined herein, which have valuable pharmacological properties, including binding to the GPR40 receptor and modulating its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
Inventors:
Eckhart Matthias
Peters Stephan
Wagner Holger
Peters Stephan
Wagner Holger
Application Number:
JP2019542787A
Publication Date:
April 08, 2022
Filing Date:
October 18, 2017
Export Citation:
Assignee:
Boehringer Ingelheim International Gesellschaft Mitt Beschlenktel Haftung
International Classes:
C07D213/74; A61K31/44; A61K31/4427; A61K31/443; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/497; A61K31/506; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/02; A61P9/04; A61P9/10; A61P9/12; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12
Domestic Patent References:
| JP2015525782A |
Foreign References:
| WO2005087710A1 | ||||
| WO2007013689A1 | ||||
| WO2005051890A1 | ||||
| WO2009054390A1 | ||||
| WO2008066097A1 | ||||
| WO2015125085A1 | ||||
| WO2004041266A1 |
Attorney, Agent or Firm:
Shinichiro Tanaka
Yoshi Kazuhiko Ta
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Yasumasa Sasaki
Yoshi Kazuhiko Ta
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Yasumasa Sasaki