Title:
BETA-LACTAM ANTIBIOTICS, MANUFACTURE AND USE
Document Type and Number:
Japanese Patent JPS5799587
Kind Code:
A
Abstract:
The present invention provides a process for inversion of the absolute stereochemistry at the alpha -carbon atom of a C-6 substituent of a bicyclic carbapenem antibiotic via a phosphorus - azodicarboxylate mediated reaction. Novel azides, amines and formates are described as useful intermediates and as antibacterial agents.
Inventors:
DEIBITSUDO FURANSHISU KORUBITS
ROBAATO SAUSUGEITO
SUTEIIBUN KOURUTON
ROBAATO SAUSUGEITO
SUTEIIBUN KOURUTON
Application Number:
JP17065181A
Publication Date:
June 21, 1982
Filing Date:
October 24, 1981
Export Citation:
Assignee:
BEECHAM GROUP LTD
International Classes:
C07D477/00; A61K31/397; A61K31/40; A61P31/04; C07D477/02; (IPC1-7): A61K31/40; C07D487/04