β-シートミメティックならびにそれに関連する組成物および方法

Title:

β-シートミメティックならびにそれに関連する組成物および方法

Document Type and Number:

Japanese Patent JP2005526722

Kind Code:

A

Abstract:

Compounds having the following structure: including pharmaceutically acceptable salts and stereoisomers thereof, wherein A, A', B, X, Y, R₂, R₃, R₄and R₅are as defined herein. Such compounds have utility over a wide range of applications, including use as diagnostic and therapeutic agents. In particular, compounds of this invention, and pharmaceutical compositions containing such compounds, are tryptase antagonists.

Inventors:

Ogbu, Cyprian Oh
Kim, fluffy
Blaskovich, Mark A.

Application Number:

JP2003567419A

Publication Date:

September 08, 2005

Filing Date:

February 14, 2003

Export Citation:

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Assignee:

Myriad Genetics, Inc.

International Classes:

A61K31/5025; A61P1/04; A61P1/16; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P27/16; A61P29/00; A61P37/08; A61P43/00; C07D487/04; C07B61/00; (IPC1-7): C07D487/04; A61K31/5025; A61P1/04; A61P1/16; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P27/16; A61P29/00; A61P37/08; A61P43/00

Domestic Patent References:

JP2002503674A

2002-02-05

Foreign References:

WO1999041276A1

1999-08-19

Attorney, Agent or Firm:

Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo

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