Title:
キナーゼ阻害剤としてのビアリールアミド化合物
Document Type and Number:
Japanese Patent JP6738369
Kind Code:
B2
Abstract:
The present invention provides compounds of Formula (I)
as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.
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Inventors:
Robert Abertha
Versanti, Paul A.
Burger, matthew
Dillon, Michael Patrick
Depesa, Alan
Hu, Chen
Lou, Yang
Nishiguchi, Giselle
Bread, yue
Polyakoff, Valery
La Mercy, Savigli
Rico, Alice
Letti
Smith, Aaron
Subramanian, Shalador
Taft, Benjamin
Tanner, Hugh
Wan, Liven
Yusuf, Naem
Versanti, Paul A.
Burger, matthew
Dillon, Michael Patrick
Depesa, Alan
Hu, Chen
Lou, Yang
Nishiguchi, Giselle
Bread, yue
Polyakoff, Valery
La Mercy, Savigli
Rico, Alice
Letti
Smith, Aaron
Subramanian, Shalador
Taft, Benjamin
Tanner, Hugh
Wan, Liven
Yusuf, Naem
Application Number:
JP2018084828A
Publication Date:
August 12, 2020
Filing Date:
April 26, 2018
Export Citation:
Assignee:
Novartis Age
International Classes:
C07D213/74; A61K31/5377; A61K31/541; A61K31/553; A61K45/00; A61P35/00; A61P43/00; C07D213/81; C07D237/20; C07D237/22; C07D237/24; C07D239/42; C07D239/47; C07D239/48; C07D241/20; C07D263/58; C07D277/42; C07D401/04; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D413/04; C07D413/12; C07D413/14; C07D417/04; C07D417/12; C07D471/04; C07D487/04; C07D491/048; C07D491/107; C07D495/04; C07D498/08; C07D513/04
Domestic Patent References:
| JP6360879B2 | ||||
| JP2010531850A | ||||
| JP2010533159A |
Foreign References:
| US6608053 | ||||
| WO2008018426A1 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Yasuhito Suzuki