Title:
ジアシルグリセロールアシルトランスフェラーゼの阻害剤としての二環式化合物
Document Type and Number:
Japanese Patent JP2012520887
Kind Code:
A
Abstract:
The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase ("DGAT") inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the invention is shown below: formula (I).
Inventors:
Zhou, Guern
Wishart, Grant
Tin, Pauline, Sea.
Aslanian, Robert, Gee.
Zone, nicholas
Cao, Jien Hoa
Wishart, Grant
Tin, Pauline, Sea.
Aslanian, Robert, Gee.
Zone, nicholas
Cao, Jien Hoa
Application Number:
JP2012500881A
Publication Date:
September 10, 2012
Filing Date:
March 16, 2010
Export Citation:
Assignee:
Schering Corporation
International Classes:
C07D209/08; A61K31/192; A61K31/404; A61K31/47; A61K31/538; A61K31/5513; A61P3/00; A61P3/04; A61P3/10; A61P43/00; C07C233/65; C07D215/50; C07D243/14; C07D265/36
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Yasufumi Shiroyama
Kenji Ando
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Yasufumi Shiroyama
Kenji Ando