Title:
BICYCLIC PHENOL ETHER, MANUFACTURE AND ANTIALLERGIC DRUG
Document Type and Number:
Japanese Patent JPS58167587
Kind Code:
A
Abstract:
The present invention provides bicyclic phenol ethers of the general formula: (I) wherein R1 is a hydrogen atom or a lower alkyl radical, R2 is a hydrogen atom or an acyl radical, X is an oxygen or sulphur atom or an -NH- group; Y is a -CO-CHR3- group or a group; R3 is a hydrogen atom, a lower alkyl radical which can be optionally substituted by an aryl radical, or a cycloalkyl radical containing 3 to 7 carbon atoms; and R4 and R5, which can be the same or different, are hydrogen atoms, lower alkyl radicals, lower alkyl radicals, alkenyl radicals containing 2 to 16 carbon atoms, which can be optionally substituted by an aryl radical, or an aryl radical; or R4 and R5, together with the carbon atom to which they are attached, form a cycloalkyl ring containing 3 to 7 carbon atoms; and the salts thereof with pharmacologically acceptable acids. The present invention also provides processes for the preparation of these compounds, as well as pharmaceutical compositions containing them.
Inventors:
BUARUTAA GUNAARU FURIIBE
BUORUFUGANGU KANPE
ANDORONIKI RETSUSHIYU
BUORUFUGANGU SHIYAUMAN
BUORUFUGANGU KANPE
ANDORONIKI RETSUSHIYU
BUORUFUGANGU SHIYAUMAN
Application Number:
JP3676683A
Publication Date:
October 03, 1983
Filing Date:
March 08, 1983
Export Citation:
Assignee:
BOEHRINGER MANNHEIM GMBH
International Classes:
A61K31/34; A61K31/40; A61K31/443; A61K31/445; A61P37/08; C07D307/83; C07D401/12; C07D405/12; (IPC1-7): A61K31/445; C07D405/12
Attorney, Agent or Firm:
Toshio Yano