Title:
BINDING AGENT INHIBITING MYOSTATIN
Document Type and Number:
Japanese Patent JP2010193888
Kind Code:
A
Abstract:
To provide a binding agent comprising a peptide binding myostatin and inhibiting its activity.
There is disclosed a binding agent comprising at least one myostatin-binding peptide attached directly or indirectly to at least one vehicle such as a polymer or an Fc domain. Therapeutic compositions containing the binding agents are useful for treating amyotrophic disorders and metabolic disorders including diabetes and obesity. There are disclosed methods for detecting and measuring myostatin and methods for diagnosing myostatin-related disorders.
Inventors:
HAN HQ
MIN HOSUNG
BOONE THOMAS CHARLES
MIN HOSUNG
BOONE THOMAS CHARLES
Application Number:
JP2010040110A
Publication Date:
September 09, 2010
Filing Date:
February 25, 2010
Export Citation:
Assignee:
AMGEN INC
International Classes:
C12N15/09; A61K38/00; A61K38/08; A61K38/10; A61K38/16; A61K38/17; A61K38/18; A61K39/395; A61K47/48; A61P3/04; A61P3/10; A61P9/04; A61P11/00; A61P13/02; A61P13/12; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P21/04; A61P29/00; A61P31/18; A61P35/00; A61P43/00; C07K7/00; C07K7/06; C07K7/08; C07K14/00; C07K14/475; C07K14/495; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/11; C12Q1/00; G01N33/53; C12Q
Domestic Patent References:
| JP2002513768A | 2002-05-14 |
Foreign References:
| WO2000024782A2 | 2000-05-04 | |||
| WO2002055544A2 | 2002-07-18 | |||
| WO2002009641A2 | 2002-02-07 |
Other References:
JPN6009043665; Ｐｒｏｃ． Ｎａｔｌ． Ａｃａｄ． Ｓｃｉ． Ｕ．Ｓ．Ａ． （２００１） ｖｏｌ．９８， ｎｏ．１６， ｐ．９３０６-９３１１
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hirose Shinobu
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hirose Shinobu
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