Title:
CD44の抗原性部分を発現する細胞の結合検査法及び単離法
Document Type and Number:
Japanese Patent JP4981448
Kind Code:
B2
Abstract:
This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.
Inventors:
Young, David, S., F.
Hahn, Susan, Yi.
Findlay, Helen, Pee.
Hahn, Susan, Yi.
Findlay, Helen, Pee.
Application Number:
JP2006523500A
Publication Date:
July 18, 2012
Filing Date:
August 20, 2004
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
G01N33/574; A61K49/00; C07K16/00; C07K16/28; C07K16/30; G01N33/569; G01N33/577
Domestic Patent References:
| JP2000502067A |
Foreign References:
| WO2003055515A1 | ||||
| US20020041877 | ||||
| WO2002094879A1 |
Other References:
PENNO MB, et al.,Expression of CD44 in Human Lung Tumors,Cancer Research,1994年 3月 1日,Vol. 54, No. 5,p. 1381-1387
Attorney, Agent or Firm:
Kazunori Saito
Tetsuya Ito
Tetsuya Ito