Title:
生体接着剤組成物及びその製造と使用
Document Type and Number:
Japanese Patent JP2004513676
Kind Code:
A
Abstract:
The present invention relates generally to the preparation and use of novel enhanced biological tissue adhesives which rely on combining fibrinogen and thrombin. More particularly, the present invention relates to a method of preparing a fibrin sealant whereby said sealant is formed by reconstituting the fibrinogen component in the presence of various critical biological and non-biological agents. The invention further relates to a novel method of using said enhanced fibrin sealant whereby the sealant and accompanying agent are delivered directly to a critical site within the body and sealed in place due to the bio-static quality of the sealant resulting in enhanced therapeutic value derived by the prolonged presence, and optionally time-released delivery, of said accompanying agent at the critical site.
Inventors:
Austin, sam, ell
Davis, Thomas, Yi
Davis, Thomas, Yi
Application Number:
JP2002503355A
Publication Date:
May 13, 2004
Filing Date:
June 22, 2001
Export Citation:
Assignee:
Austin, sam, ell
Davis, Thomas, Yi
Davis, Thomas, Yi
International Classes:
A61K9/10; A61K31/57; A61K35/12; A61K45/00; A61K47/42; A61K48/00; A61L24/00; A61L24/10; A61L26/00; A61L27/22; A61L31/04; A61P7/04; A61P29/00; C09J189/00; (IPC1-7): A61L26/00; A61K9/10; A61K31/57; A61K35/12; A61K45/00; A61K47/42; A61K48/00; A61P7/04; A61P29/00; C09J189/00
Domestic Patent References:
| JPH0940579A | 1997-02-10 | |||
| JPH05970A | 1993-01-08 | |||
| JPS5836545A | 1983-03-03 |
Foreign References:
| WO1995022316A1 | 1995-08-24 |
Attorney, Agent or Firm:
Kaoru Furuya
Takahiko Mizobe
Satoshi Furuya
Kiyoharu Nishiyama
Takahiko Mizobe
Satoshi Furuya
Kiyoharu Nishiyama