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Title:
BIODEGRADABLE CELLULOSE NANOFIBER MICROGEL, BIODEGRADABLE CELLULOSE NANOFIBER GEL AND MANUFACTURING METHOD OF BIODEGRADABLE CELLULOSE NANOFIBER SHEET
Document Type and Number:
Japanese Patent JP2016210893
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a material capable of being used as a scaffold material for tissue engineering and a medical material such as a carrier for a drug delivery system and capable of existing stably in organism by suppressing biodegradation efficiently without using a chemical crosslinking agent such as glutaraldehyde.SOLUTION: There is provided a manufacturing method of a biodegradable cellulose nanofiber microgel including a process for adding a cellulose nanofiber dispersion in a strong alkali solution with stirring to prepare a cellulose nanofiber strong alkali dispersion, a process for stirring the cellulose nanofiber strong alkali dispersion after adding to a liquid paraffin containing a surfactant with stirring to prepare a cellulose nanofiber microgel dispersion, a process for adding acid and an organic solvent to the cellulose nanofiber microgel dispersion, then standing it, naturalizing the cellulose nanofiber microgel dispersion to remove the liquid paraffin and a process for impregnating the cellulose nanofiber microgel into NaIOsolution to add biodegradability.SELECTED DRAWING: None

Inventors:
MATSUMURA KAZUAKI
TANAKA HIROYUKI
YOKOKURA YUSUKE
Application Number:
JP2015095925A
Publication Date:
December 15, 2016
Filing Date:
May 08, 2015
Export Citation:
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Assignee:
JAPAN ADVANCED INST OF SCIENCE & TECH HOKURIKU
CHUETSU PULP IND
International Classes:
C08B15/02; A61K9/06; A61K9/70; A61K47/38; A61L27/00; B82Y5/00; B82Y40/00; C08B1/08; C08J5/18
Domestic Patent References:
JP2010235687A2010-10-21
JP2015048467A2015-03-16
JP2014118521A2014-06-30
Foreign References:
WO2011068023A12011-06-09
Other References:
CARBOHYDRATE POLYMERS, vol. 85, no. 4, JPN6019024404, 2011, pages 733 - 737, ISSN: 0004238987
神野 和人: "セルロースナノファイバーの高機能化技術(増粘・ゲル化)", BIO INDUSTRY, vol. 30, no. 9, JPN6019024406, 2013, pages 29 - 36, ISSN: 0004238988
セルロースの事典, JPN6019024409, 10 November 2000 (2000-11-10), pages 336 - 337, ISSN: 0004238989
原 一広: "生分解性を有するカルボキシルメチルセルロースゲルの環境浄化への利用の試み", 2004年(平成16年)春季 第51回応用物理学関係連合講演会講演予稿集 第1分冊, JPN6019024413, 2004, pages 474, ISSN: 0004238990
MATERIALS SCIENCE AND ENGINEERING C, vol. 29, no. 5, JPN6019024408, 2009, pages 1635 - 1642, ISSN: 0004238991
Attorney, Agent or Firm:
Axis International Patent Business Corporation
Hiroyuki Koitabashi