Title:
神経精神ループスを検出するためのバイオマーカー
Document Type and Number:
Japanese Patent JP7320863
Kind Code:
B2
Abstract:
In one embodiment, the present invention addresses the problem of providing: a maker for detecting NPSLE; or a method for detecting NPSLE using the marker. In one embodiment, the present invention relates to a biomarker for detecting NPSLE or a biomarker for determining a therapeutic effect on NPSLE, wherein the biomarker comprises galectin-9 protein or a peptide fragment thereof or a transcript of galectin-9 gene or a nucleotide fragment thereof. In one embodiment, the present invention relates to a method for assisting the determination as to whether or not a subject animal is affected by NPSLE or as to the presence or absence of NPSLE incidence risk, a method for assisting the determination of a therapeutic effect on NPSLE, or a kit for detecting NPSLE, in each of which the biomarker is used.
Inventors:
Kiyoshi Umeda
Naoki Matsuoka
Tomoyuki Asano
Naoki Matsuoka
Tomoyuki Asano
Application Number:
JP2021526841A
Publication Date:
August 04, 2023
Filing Date:
June 17, 2020
Export Citation:
Assignee:
Fukushima Medical University
International Classes:
C12Q1/6813; C12Q1/6844; G01N33/53
Other References:
galectin-9 isoform [Homo sapiens],GenBank: BAA22166.1 [online],2009年03月10日,[検索日 2020.8.21], インターネット
Rheumatology,2013年,Vol.52, p.2218-2222
ARTHRITIS & RHEUMATISM,2007年,Vol.56, No.4, p.1242-1250
Annals of the Rheumatic Diseases,2018年,Vol.77, p.1810-1814
Rheumatology,2013年,Vol.52, p.2218-2222
ARTHRITIS & RHEUMATISM,2007年,Vol.56, No.4, p.1242-1250
Annals of the Rheumatic Diseases,2018年,Vol.77, p.1810-1814
Attorney, Agent or Firm:
Patent Attorney Corporation Hiraki International Patent Office
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