Title:
BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH
Document Type and Number:
Japanese Patent JP2023164722
Kind Code:
A
Abstract:
To provide biomarker panels, methods and kits for determining the probability for preterm birth in a pregnant female.SOLUTION: The present disclosure is based, in part, on the discovery that certain proteins and peptides in biological samples obtained from a pregnant female are differentially expressed in pregnant females that have an increased risk of developing preterm birth in the future or presently suffering from preterm birth relative to matched controls. The present disclosure is further based, in part, on the unexpected discovery that panels combining one or more of these proteins and peptides can be utilized in methods of determining the probability for preterm birth in a pregnant female with relatively high sensitivity and specificity.SELECTED DRAWING: None
Inventors:
DURLIN EDWARD HICKOK
JOHN JAY BONIFACE
GREGORY CHARLES CRITCHFIELD
TRACEY CRISTINE FLEISCHER
JOHN JAY BONIFACE
GREGORY CHARLES CRITCHFIELD
TRACEY CRISTINE FLEISCHER
Application Number:
JP2023158198A
Publication Date:
November 10, 2023
Filing Date:
September 22, 2023
Export Citation:
Assignee:
SERA PROGNOSTICS INC
International Classes:
G01N33/68; C07K14/46
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto