Title:
(ビフェニル)カルボン酸およびその誘導体
Document Type and Number:
Japanese Patent JP5054532
Kind Code:
B2
Abstract:
The present invention relates to compounds having the general formula (I) with the definitions of R 1 -R 6 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds as a medicament, preferably for the treatment of Alzheimer's disease and their use for the modulation of ³-secretase activity.
Inventors:
Wilson Francis
Raid Allison
Leader valery
Harrison Richard John
Miyu Sunase
Hernandez-Perni Remedios
Major Jeremy
Bossard Cyril
Smelt Catherine
Taylor jess
Reformal Adeline
Cansfield andrew
Back hard svenir
Raid Allison
Leader valery
Harrison Richard John
Miyu Sunase
Hernandez-Perni Remedios
Major Jeremy
Bossard Cyril
Smelt Catherine
Taylor jess
Reformal Adeline
Cansfield andrew
Back hard svenir
Application Number:
JP2007537225A
Publication Date:
October 24, 2012
Filing Date:
October 21, 2005
Export Citation:
Assignee:
Cellsome Limited
International Classes:
C07C59/68; A61K31/192; A61K31/351; A61K31/40; A61K31/42; A61K31/5375; A61P25/28; A61P43/00; C07C51/09; C07C51/353; C07C62/12; C07C67/343; C07C69/734; C07C69/757; C07C231/12; C07C233/54; C07C235/42; C07C303/40; C07C311/29; C07C315/04; C07C317/22; C07D261/08; C07D295/16; C07D295/22; C07D309/06; C07B57/00; C07B61/00
Domestic Patent References:
| JP2006518351A |
Foreign References:
| WO2004073705A1 | ||||
| US20020128319 | ||||
| WO2006048219A1 | ||||
| WO2006008558A1 | ||||
| WO2004064771A2 |
Other References:
Tamura, Yasumitsu et al.,Nonsteroidal antiinflammatory agents. 1. 5-Alkoxy-3-biphenylylaceticacids and related compounds as new potential antiinflammatory agents,Journal of Medicinal Chemistry,1977年,Vol.20,No.5,p.709-14
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki