Title:
BISCONJUGATE COMPRISING TWO SACCHARIDES AND ONE SPACER
Document Type and Number:
Japanese Patent JP3918953
Kind Code:
B2
Abstract:
PURPOSE: To provide a tunable bisconjugate that comprises two saccharides which contain a plurality of monosaccharide units, at least one unit being uronic acid, and a spacer, and the spacer links one saccharide to the other saccharide at a non-reductive terminal and is useful for treating thrombosis.
CONSTITUTION: This objective bisconjugate comprises two saccharides and a spacer, each saccharide being the same or different and comprising two to six mono-saccharide units, at least one unit being uronic acid, characterized in that at least one of the saccharides per se has anti-thrombotic activity, and that the spacer connects at least one saccharide to the other through its non- reducing end, the chain length of the spacer being 20-120 atoms.
Inventors:
Constant Adrian Anton Juan Boker
Peter Dayderick Jan Glutenhuis
Maurice Putito
Peter Westerdyne
Peter Dayderick Jan Glutenhuis
Maurice Putito
Peter Westerdyne
Application Number:
JP23200394A
Publication Date:
May 23, 2007
Filing Date:
September 01, 1994
Export Citation:
Assignee:
Sanofi-Aventis
International Classes:
C07H7/033; C07H15/18; A61K31/70; A61K31/7012; A61K31/7028; A61K47/48; A61P7/02; A61P43/00; C07H3/06; C07H7/04; C07H11/00; C07H13/00; C07H15/04; C07H15/08; C07H15/22; C07H15/26; C07K9/00; C08B37/00; C08B37/10; A61K; C07H; (IPC1-7): C07H7/033; A61K31/70; A61K31/70; C08B37/00
Domestic Patent References:
| JP6366192A | ||||
| JP1143890A | ||||
| JP245496A | ||||
| JP2206601A |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
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