BLOOD LIPID LOWERING PARAAAMINOBENZOIC ACIDS

Title:

BLOOD LIPID LOWERING PARAAAMINOBENZOIC ACIDS

Document Type and Number:

Japanese Patent JPS5289660

Kind Code:

A

Abstract:

Schiff's bases of the formula I in which R is hydrogen or lower alkyl are obtained by reacting piperonal with p-aminobenzoic acid or with a p-aminobenzoic ester. 4-(1,3-Benzodioxol-5-ylmethylamino)benzoic acid and 4-(1,3-benzodioxol-5-ylmethylamino)benzoic esters of the formula II in which R is hydrogen or lower alkyl are obtained by reducing Schiff's bases of the formula I. The compound 4-(1,3-benzodioxol-5-ylmethylamino)benzoic acid which can be prepared according to the invention can be used, for example, for the reduction of the lipid level in the plasma of animals.

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Inventors:

YUUJIIN ROSU WAGUNAA
BOBII JIYUERU AREN
ARUFURETSUDO AASAA RENJI

Application Number:

JP384477A

Publication Date:

July 27, 1977

Filing Date:

January 17, 1977

Export Citation:

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Assignee:

DOW CHEMICAL CO

International Classes:

A61K31/195; A61K31/245; A61K31/357; A61K31/36; A61P3/06; C07C67/00; C07C227/00; C07C229/60; C07D317/58; (IPC1-7): A61K31/195; A61K31/36; C07C101/56; C07D317/58

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