Title:
グリコマクロペプチド由来の血圧降下ペプチド
Document Type and Number:
Japanese Patent JP5770411
Kind Code:
B2
Abstract:
A process to produce IPP from a protein source whereby the protein source comprises a protein having the -I-P-P- sequence and having in the protein amino acid sequence at least 6 times more -I-P-P- present than -V-P-P- (molar basis) which comprises hydrolysing the protein source to liberate at least 40% of the I-P-P- sequence into the peptide IPP and whereby a proteolytic enzyme is used which cleaves at the carboxy-terminus of proline residues present in the protein source, the enzyme is preferably a proline specific endoprotease or proline specific oligopeptidase, more preferably a proline specific endoprotease, and optionally an amino peptidase.
Inventors:
Ruth, De Andre Leonardus
Broke, Van den Peter Marinus
Eden's, Ruppo
Broke, Van den Peter Marinus
Eden's, Ruppo
Application Number:
JP2007556603A
Publication Date:
August 26, 2015
Filing Date:
February 23, 2006
Export Citation:
Assignee:
DSM IP ASSETS B.V.
International Classes:
C12P21/06; A23K1/16; A23K1/18; A23L1/305; A61K9/06; A61K9/10; A61K9/107; A61K31/4415; A61K31/714; A61K38/00; A61P3/04; A61P3/06; A61P3/10; A61P9/04; A61P9/12; A61P25/08; A61P43/00; C07K5/10
Domestic Patent References:
| JP2001136995A |
Foreign References:
| WO2003102195A1 |
Other References:
Br.J.Nutr.,2000年,Vol.84,Suppl.1,S39-S46
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Yoshinori Shimizu
Ikeda adult
Kazuhiro Yamaguchi
Kimoto
Hiroto Kido
Masato Ikeda
Masakazu Noda
Yoshinori Shimizu
Ikeda adult
Kazuhiro Yamaguchi
Kimoto
Hiroto Kido
Masato Ikeda