BORON NEUTRON CAPTURING AGENT OF NANO-SILICA PARTICLES CONTAINING BORON ISOTOPE

Title:

BORON NEUTRON CAPTURING AGENT OF NANO-SILICA PARTICLES CONTAINING BORON ISOTOPE

Document Type and Number:

Japanese Patent JP2019163229

Kind Code:

A

Abstract:

To provide a drug transport (delivery) material with excellent specific accumulation property to tumor cells or cancer cells which is produced by chemically bonding oligosaccharide and oligopeptide, which are excellent in specific binding properties to tumor cells or cancer cells and can be easily and simply produced, to boron isotope nano-silica particles, for boron neutron capture therapy (BNCT).SOLUTION: Boron isotopes are first chemically bonded to nano-silica particles, and oligosaccharide and oligopeptide are further bonded while considering selectivity and accumulation property to various types of tumor cells or cancer cells, and BNCT is complete.SELECTED DRAWING: Figure 1

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Inventors:

HORI HITOSHI
TOKUNAGA HIKO
TAKAHASHI MASAO

Application Number:

JP2018072734A

Publication Date:

September 26, 2019

Filing Date:

March 19, 2018

Export Citation:

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Assignee:

DYNAMIC SCIENCE CORP
HORI HITOSHI
TOKUNAGA HIKO

International Classes:

A61K47/69; A61K41/00; A61K51/08; A61K51/12; A61P35/00; C07B59/00; C07F5/02; C07K5/103; C07K7/06

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