Title:
ホウ素化金属フタロシアニン、その調製方法、これを有する薬学的組成物及びその使用方法
Document Type and Number:
Japanese Patent JP4968673
Kind Code:
B2
Abstract:
The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.
Inventors:
Roncucci Gabrio
Joli Giulio
Guntini Francesca
Fabrice Clara
Chiti Giacomo
Munich Moira
Day Donata
Joli Giulio
Guntini Francesca
Fabrice Clara
Chiti Giacomo
Munich Moira
Day Donata
Application Number:
JP2006504641A
Publication Date:
July 04, 2012
Filing Date:
March 11, 2004
Export Citation:
Assignee:
El Morteni and C. dei Fratelli Alic Societa'die Sertizio Societa Peratini
International Classes:
C07F5/02; A61K31/555; A61K41/00; A61P35/00; C07C255/54; C07C317/18; C07D487/22; C07F5/06; C07F7/02; C09B47/04; C09B47/067; C09B47/08; C07B59/00; C07F3/06
Domestic Patent References:
| JP8225751A |
Foreign References:
| US3730950 |
Other References:
FABRIS,C. et al,Photosensitizing properties of a boronated phthalocyanine: studies at the molecular and cellular level,Journal of Photochemistry and Photobiology, B: Biology,2001年,Vol.64, No.1,p.1-7
KAHL,S.B. et al,Synthesis and Characterization of a Boronated Metallophthalocyanine for Boron Neutron Capture Therapy,Inorganic Chemistry,1996年,Vol.35, No.13,p.3878-3880
KAHL,S.B. et al,Synthesis and Characterization of a Boronated Metallophthalocyanine for Boron Neutron Capture Therapy,Inorganic Chemistry,1996年,Vol.35, No.13,p.3878-3880
Attorney, Agent or Firm:
Michio Nagai