BORYLATED MULTIFUNCTIONAL TARGETING DRUG CONJUGATES, USES THEREOF, AND METHODS FOR PREPARATION THEREOF

Title:

BORYLATED MULTIFUNCTIONAL TARGETING DRUG CONJUGATES, USES THEREOF, AND METHODS FOR PREPARATION THEREOF

Document Type and Number:

Japanese Patent JP2023055763

Kind Code:

A

Abstract:

To provide multifunctional constructs that can selectively target and deliver cargo to cells such as cancer cells, by using as a platform certain B-complexes displaying suitable properties of stability and controlled reversibility.SOLUTION: Provided is a multifunctional compound comprising a tripodal borylated core, which has (a) at least one therapeutically useful cargo molecule, (b) at least one water-soluble moiety or a residue drug of a water-soluble molecule, (c) at least one functionalizing moiety, and (d) at least one targeting unit.SELECTED DRAWING: None

Inventors:

Gois, Pedro
Fabio, Santos

Application Number:

JP2023007329A

Publication Date:

April 18, 2023

Filing Date:

January 20, 2023

Export Citation:

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Assignee:

Hobione Scientia Limited

International Classes:

C07F5/02; A61K31/69; A61P19/02; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P35/00

Attorney, Agent or Firm:

Tsugu Nishiura Haru
Tadashi Ideyama

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