PURPOSE: To obtain a brain metabolism promoting and memory improving agent containing a substance with active oxygen scavenging action as a main ingredient.
CONSTITUTION: This brain metabolism promoting and memory improving agent consists essentially of an active oxygen scavenging substance one of whom is a nitrone compound, e.g. α-phenyl-N-buthylnitrone, 5,5-dimethylpyrroline N- oxide, α-4-pyridyl-1-oxide-t-butylnitrone or a nitroso compound, e.g. t- nitrosobutane or t-butylnitrosobenzene or mixture of one or more of these substances. This compound can activate brain metabolism of aged persons such as metabolism of neurotransmitter and that of proteins, etc., to improve memorizing function and nerve function and is effective for treatment or improvement of cerebral circulation disorders, e.g. cerebral thrombosis, cerebral embolism, cerebral infarction, cerebral hemorrhage and cerebral arteriosclerosis of mammal including human or brain and nerve diseases, e.g. dysmnesia, geriatric dementia and Parkinson's disease which frequently occur in aged persons.
NAKANO MASATOSHI
RICHIYAADO GEIRU KATORAA