Title:
Bruton's tyrosine kinase inhibitor
Document Type and Number:
Japanese Patent JP6345786
Kind Code:
B2
Abstract:
Disclosed herein are reversible and irreversible inhibitors of Bruton's tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are described, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
Inventors:
Jia, Chaochon, Jay.
Thomas, William, Dee.
Chain way
Thomas, William, Dee.
Chain way
Application Number:
JP2016536548A
Publication Date:
June 20, 2018
Filing Date:
December 03, 2014
Export Citation:
Assignee:
Pharma Cyclics LLC
International Classes:
C07D401/04; A61K31/497; A61K31/513; A61K31/53; A61K31/5377; A61K31/541; A61K31/55; A61P17/02; A61P19/02; A61P19/08; A61P19/10; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04
Domestic Patent References:
| JP2011526299A | ||||
| JP2012529535A |
Foreign References:
| WO2013047813A1 | ||||
| US20130131040 |
Attorney, Agent or Firm:
Kazuhiro Kiyohara