Title:
A CD3 joint molecule combinable with humans and nonhuman CD3
Document Type and Number:
Japanese Patent JP6141831
Kind Code:
B2
Abstract:
The present invention relates to CD3 -binding molecules capable of binding to human and non-human CD3, and in particular to such molecules that are cross-reactive with CD3 of a non-human mammal (e.g., a cynomolgus monkey). The invention also pertains to uses of such antibodies and antigen-binding fragments in the treatment of cancer, autoimmune and/or inflammatory diseases and other conditions.
Inventors:
Fan, lin
Johnson, Leslie S.
Johnson, Leslie S.
Application Number:
JP2014512882A
Publication Date:
June 07, 2017
Filing Date:
May 16, 2012
Export Citation:
Assignee:
Macrogenics, Incorporated
International Classes:
C07K16/28; A61K39/395; A61P1/14; A61P3/06; A61P3/10; A61P5/14; A61P11/02; A61P11/06; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P29/00; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P37/08; C07K16/46
Domestic Patent References:
| JP2009511521A | ||||
| JP2010524851A | ||||
| JP2010524435A |
Attorney, Agent or Firm:
Takaaki Nagashima
Shunsuke Wakayama
Shunsuke Wakayama
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