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Title:
抗高血圧剤との組み合わせのCETP阻害剤及びその使用
Document Type and Number:
Japanese Patent JP2005538977
Kind Code:
A
Abstract:
This invention relates to pharmaceutical combinations of a cholesteryl ester transfer protein (CETP) inhibitor or a pharmaceutically acceptable salt thereof; and an antihypertensive agent or a pharmaceutically acceptable salt thereof, optionally in combination with an HMG CoA reductase inhibitor or a pharmaceutically acceptable salt thereof, kits containing such combinations and methods of using such combinations to treat subjects suffering from atherosclerosis, peripheral vascular disease, dyslipidemia, hyperbetaliproteinemia, hypoalphalipoproteinemia, hypercholesterolemia, hypertriglyceridemia, familial-hypercholesterolemia, cardiovascular disorders, angina, ischemia, cardiac ischemia, stroke, myocardial infarction, reperfusion injury, angioplastic restenosis, hypertension, vascular complications of diabetes, obesity or endotoxemia in a mammal (including a human being either male or female).

Inventors:
Ruggeli, Roger Benjamin
Application Number:
JP2004519070A
Publication Date:
December 22, 2005
Filing Date:
June 20, 2003
Export Citation:
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Assignee:
Pfizer Products Inc.
International Classes:
A61K31/00; A61K31/275; A61K31/40; A61K31/401; A61K31/403; A61K31/4178; A61K31/4422; A61K31/47; A61K31/4706; A61K31/4965; A61K31/517; A61K31/554; A61K45/06; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/08; A61P9/10; A61P9/12; (IPC1-7): A61K45/06; A61K31/275; A61K31/40; A61K31/401; A61K31/403; A61K31/4178; A61K31/4422; A61K31/4706; A61K31/4965; A61K31/517; A61K31/554; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/08; A61P9/10; A61P9/12
Domestic Patent References:
JP2001242173A2001-09-07
JP2001206845A2001-07-31
JP2002179558A2002-06-26
JP2001514223A2001-09-11
JP2002509540A2002-03-26
JP2001288115A2001-10-16
Foreign References:
WO2000017165A12000-03-30
WO2002047678A12002-06-20
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama