Title:
COMT阻害剤
Document Type and Number:
Japanese Patent JP2009544571
Kind Code:
A
Abstract:
New compounds of formula I are described: The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders.
Inventors:
Rearmans, david, alexander
Kiss, Rasulo, Erno
Real, Palma, Pedro, Newno
Dos Santos Ferreira, Humberto
Araujo Soares da Silva, Patricio Manuel Vieira
Kiss, Rasulo, Erno
Real, Palma, Pedro, Newno
Dos Santos Ferreira, Humberto
Araujo Soares da Silva, Patricio Manuel Vieira
Application Number:
JP2008523836A
Publication Date:
December 17, 2009
Filing Date:
July 26, 2006
Export Citation:
Assignee:
Vials-Portella and CA, S.A.
International Classes:
C07D213/89; A61K31/4245; A61K31/44; A61K31/443; A61K31/4439; A61K31/4709; A61K31/5377; A61K31/541; A61P1/04; A61P9/12; A61P25/00; A61P25/16; A61P27/02; A61P43/00; C07D271/06; C07D401/04; C07D405/04; C07D413/04; C07D413/14; C07D417/04
Domestic Patent References:
| JPS62240649A | 1987-10-21 | |||
| JPS63150237A | 1988-06-22 |
Foreign References:
| EP1167342A1 | 2002-01-02 |
Other References:
JPN5008010728; ＴＥＲＶＯ，Ａ．Ｊ． ｅｔ ａｌ: 'Ａ ｓｔｒｕｃｔｕｒｅ-ａｃｔｉｖｉｔｙ ｒｅｌａｔｉｏｎｓｈｉｐ ｓｔｕｄｙ ｏｆ ｃａｔｅｃｈｏｌ-Ｏ-ｍｅｔｈｙｌｔｒａｎｓｆｅｒａｓｅ ｉｎｈｉｂｉｔｏｒｓ ｃｏｍｂｉｎｉｎｇ ｍｏｌｅｃｕｌ' Ｊｏｕｒｎａｌ ｏｆ Ｃｏｍｐｕｔｅｒ-Ａｉｄｅｄ Ｍｏｌｅｃｕｌａｒ Ｄｅｓｉｇｎ Ｖｏｌ．１７， Ｎｏ．１２, 2003, ｐ．７９７-８１０
JPN6012007816; ＬＥＡＲＭＯＮＴＨ，Ｄ．Ａ． ｅｔ ａｌ: 'Ｃｈｅｍｉｃａｌ Ｓｙｎｔｈｅｓｉｓ ａｎｄ Ｃｈａｒａｃｔｅｒｉｚａｔｉｏｎ ｏｆ Ｃｏｎｊｕｇａｔｅｓ ｏｆ ａ Ｎｏｖｅｌ Ｃａｔｅｃｈｏｌ-Ｏ-ｍｅｔｈｙｌｔｒａｎｓｆｅｒａｓｅ Ｉｎｈｉｂｉ' Ｂｉｏｃｏｎｊｕｇａｔｅ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１３， Ｎｏ．５, 2002, ｐ．１１１２-１１１８
JPN6012007816; ＬＥＡＲＭＯＮＴＨ，Ｄ．Ａ． ｅｔ ａｌ: 'Ｃｈｅｍｉｃａｌ Ｓｙｎｔｈｅｓｉｓ ａｎｄ Ｃｈａｒａｃｔｅｒｉｚａｔｉｏｎ ｏｆ Ｃｏｎｊｕｇａｔｅｓ ｏｆ ａ Ｎｏｖｅｌ Ｃａｔｅｃｈｏｌ-Ｏ-ｍｅｔｈｙｌｔｒａｎｓｆｅｒａｓｅ Ｉｎｈｉｂｉ' Ｂｉｏｃｏｎｊｕｇａｔｅ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１３， Ｎｏ．５, 2002, ｐ．１１１２-１１１８
Attorney, Agent or Firm:
Seiji Ohno
Koji Morita
Reiko Tanaka
Ken Kitano
Natsuki Ito
Koji Morita
Reiko Tanaka
Ken Kitano
Natsuki Ito