CROSSLINKED NUCLEIC ACID GuNA, METHOD FOR PRODUCING THE SAME, AND INTERMEDIATE COMPOUND

Title:

CROSSLINKED NUCLEIC ACID GuNA, METHOD FOR PRODUCING THE SAME, AND INTERMEDIATE COMPOUND

Document Type and Number:

Japanese Patent JP2023075302

Kind Code:

A

Abstract:

To provide guanidine crosslinked artificial nucleic acid.SOLUTION: The present invention provides a compound represented by general formula VIII in the figure or a salt thereof. [In the formula, B is a base moiety of nucleic acid optionally substituted with one or more substituents; R12 is a Bn group, DMTr group, or TMS group; R13 is a Bn group, hydrogen atom, or TMS group; and m is an integer from 1 to 3.]SELECTED DRAWING: None

Inventors:

Satoshi Obiga
Eiji Kawanishi
Hiroaki Sawamoto
Shuhei Yamakoshi
Yuki Arai
Shinji Kumagai

Application Number:

JP2023041934A

Publication Date:

May 30, 2023

Filing Date:

March 16, 2023

Export Citation:

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Assignee:

Mitsubishi Tanabe Pharma Corporation
National University Corporation Osaka University

International Classes:

C07H19/06; C07H9/06; C07H19/16

Attorney, Agent or Firm:

Norito Yamao
Sei Morimoto
Nobuhiko Akiyama

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