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Title:
CANCER VACCINE CONTAINING CANCER ANTIGEN BASED ON PRODUCT OF ANTIONCOGENE WT1 AND CATIONIC LIPOSOME
Document Type and Number:
Japanese Patent JP2009079054
Kind Code:
A
Abstract:

To provide a new cancer vaccine containing a cancer antigen based on a product of an antioncogene WT1 against a Wilms' tumor and lipofectin.

The cancer vaccine containing the cancer antigen having a product of the antioncogene WT1 or its partial peptide as an active component and cationic liposome is provided. As the cationic liposome, liposome and lipofectin are selected which contain N-[1-(2,3-dioleyloxy)propyl]-N, N, N-trimethylammonium chloride, N-[1-(2,3-dioleyloxy)propyl]-N, N, N-trimethylammoniummethyl sulfate or dioctadecylamide-glycylspermine or a mixture of these compounds and a neutral fat.


Inventors:
MAYUMI TADANORI
SUGIYAMA HARUO
OSUGI YOSHIYUKI
Application Number:
JP2008259018A
Publication Date:
April 16, 2009
Filing Date:
October 03, 2008
Export Citation:
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Assignee:
MAYUMI TADANORI
SUGIYAMA HARUO
CHUGAI PHARMACEUTICAL CO LTD
International Classes:
A61K39/00; A61K9/00; A61K9/127; A61K45/08; A61K47/14; A61K47/18; A61K47/24; A61P35/00; A61P35/02; C07K14/47
Foreign References:
WO2000006602A12000-02-10
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Masaya Nishiyama