Title:
CARBODIIMIDE COMPOUND CONTAINING FLUORESCENT GROUP
Document Type and Number:
Japanese Patent JP3851706
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain the subject new compound having carbodiimide group and fluorescent group, highly sensitive to a nucleic acid (derived from nature), capable of readily and efficiently labeling in a short time and useful as a label for detection of nucleic acid and immunoassay.
SOLUTION: This new carbodiimide compound is represented by a compound of formula I {F is a fluorescent group; A is CH,, NHCO, O, etc.; W is a direct bond or ammonium group; Y1 to Y3 are each a group of the formula (CH2)p- L-(CH2)q [L is a direct bond, NHCO, O, etc.; (p) and (q) are each 0-12]; B is H or a group of the formula W-Y1 [A]n-F [(n) is 0 or 1], e.g. a compound of formula II. The compound of formula I is obtained by reacting a compound of the formula B-Y3-N=C=N-Y2-W' [W' is a (substituted) amino] with a compound of the formula F-A-Y1-X [X is a halogen or sulfonic acid group).
Inventors:
Suzuki Osamu
Masuda Gen
Namiko Shiohata
Kazuko Matsumoto
Masuda Gen
Namiko Shiohata
Kazuko Matsumoto
Application Number:
JP12263897A
Publication Date:
November 29, 2006
Filing Date:
May 13, 1997
Export Citation:
Assignee:
Nisshinbo Corporation
International Classes:
C07C267/00; G01N33/533; C07D271/08; C07D277/66; C07D311/16; C07D413/06; C07D417/06; C07D487/14; C09K11/06; C09K11/07; C12Q1/68; (IPC1-7): C09K11/06; C07D271/08; C07D277/66; C07D311/16; C07D413/06; C07D417/06; C07D487/14; C12Q1/68; G01N33/533
Domestic Patent References:
| JP6271581A | ||||
| JP58066851A | ||||
| JP3583489B2 | ||||
| JP9328620A |
Foreign References:
| US4895955 |
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Tsutomu Toyama
Hidemi Matsukura
Tsutomu Toyama
Previous Patent: PACKAGING BAG FOR HEAT-INSULATING FOOD
Next Patent: CENTRAL PROCESSING UNIT OF SUPERSCALAR PROCESSOR
Next Patent: CENTRAL PROCESSING UNIT OF SUPERSCALAR PROCESSOR