CARBOLINE DERIVATIVE - NIPPON CHEMIPHAR CO

Title:

CARBOLINE DERIVATIVE

Document Type and Number:

Japanese Patent JPH10130269

Kind Code:

A

Abstract:

To obtain the subject new derivative excellent in inhibitory action on glutamic acid toxicity, useful as a medicine for activating and improving cerebral metabolism, producible from an actinomyces belonging to the genus Streptomyces.

This derivative is shown by the formula. The derivative is obtained by culturing a strain (FERM BP-5,637) of an actinomyces belonging to the genus Streptomyces in a proper medium. The compound has, for example, the following physical and chemical properties. Appearance: reddish brown. Melting point: 247-249°C. Specific rotatory power: [α]20D=-33° (c=0.04, methanol). Molecular formula: C21H20N2O8. Molecular weight: 429.1324 (measured value), 429.1298 (calculated value). etc.

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Inventors:

SETO HARUO
ARAYA KAZUO

Application Number:

JP25753997A

Publication Date:

May 19, 1998

Filing Date:

September 04, 1997

Export Citation:

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Assignee:

NIPPON CHEMIPHAR CO

International Classes:

A61K31/55; A61P9/00; A61P43/00; C07D471/04; C12N1/20; C12P17/18; C12R1/465; (IPC1-7): C07D471/04; A61K31/55; C12N1/20; C12P17/18

Attorney, Agent or Firm:

Yasuo Yanagawa

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