カロチンシンターゼ遺伝子およびその用途

Japanese Patent JP4331103

B2

Described herein is a novel three domain gene from Schizochytrium, denoted carotene synthase, that encodes a protein with three different enzymatic activities; phytoene dehydrogenase (PD), phytoene synthase (PS), and lycopene cyclase (LC). Also described is the isolated gene encoding the carotene synthase, homologues thereof, the enzyme encoded by such gene, biologically active portions and homologues thereof and fusion proteins comprising said enzyme portions and homologues, recombinant nucleic acid molecules, microorganisms and plants that have been genetically modified to increase or decrease the action of such gene, and methods of producing carotenoids and derivatives thereof. Also described are methods of producing microorganisms and products comprising lipids lacking pigmentation using the knowledge of the carotene synthase described herein and products of said methods.

Weber Craig A.
Mets James G.
Kunel Jerry M.
Overton Frank H. Jr.

JP2004506457A

September 16, 2009

May 14, 2003

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Martech Biosciences Corporation

A01H5/00; C12N15/09; A23L1/30; A61K36/02; A61K38/44; A61K38/51; A61K38/53; A61K48/00; A61P27/02; C07K16/40; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/00; C12N9/02; C12P5/02; C12P7/00; C12P7/64

WO2001000805A2

Proceedings of the National Academy of Sciences,2001年 2月,Vol. 98, No. 4,pp. 1687-1692
European Journal of Biochemistry,2000年,Vol. 267,pp. 5509-5519
The Journal of Bacteriology,1997年,Vol. 179, No. 22,pp. 7135-7155

Hatsushi Shimizu
Koichi Niimi

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