Title:
カルベジロール塩、対応する組成物、送達および/または治療方法
Document Type and Number:
Japanese Patent JP2007512372
Kind Code:
A
Abstract:
The present invention relates to a salt of carvedilol and/or corresponding solvates thereof, compositions containing such carvedilol and/or corresponding solvates thereof, and/or methods of using the aforementioned compound(s) in the treatment of certain disease states in mammals, in particular man. The present invention further relates to carvedilol phosphate salts, and/or solvates thereof, which include a novel crystalline form of carvedilol dihydrogen phosphate (i.e., which is the dihydrogen phosphate salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol) and/or carvedilol hydrogen phosphate, etc.) and/or other corresponding solvates thereof, compositions containing these carvedilol phosphate salts and/or solvates, and methods of using the aforementioned salts and/or solvates to treat hypertension, congestive heart failure and angina, etc.
Inventors:
Christopher S. Brook
Pin Yun Yi Chen
Chen Wei
Kung In Die
Philip Sea Delorco
Claire Islet
David H. I Go
Lee M Catrinsic
Clifford S. Lavo
Anne Marie Diederick
Jung Kai Oh
Lee Gen Pin
Paul G. Spurs
Wan Jun
Christopher Warner
Pin Yun Yi Chen
Chen Wei
Kung In Die
Philip Sea Delorco
Claire Islet
David H. I Go
Lee M Catrinsic
Clifford S. Lavo
Anne Marie Diederick
Jung Kai Oh
Lee Gen Pin
Paul G. Spurs
Wan Jun
Christopher Warner
Application Number:
JP2006541702A
Publication Date:
May 17, 2007
Filing Date:
November 24, 2004
Export Citation:
Assignee:
SB Pharmco Puerto Rico Inc
International Classes:
C07D209/88; A61K31/403; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P43/00; C07D209/82
Domestic Patent References:
| JP2003514019A | 2003-04-15 | |||
| JP2001510824A | 2001-08-07 | |||
| JP2005534716A | 2005-11-17 | |||
| JP2005533823A | 2005-11-10 | |||
| JP2005533822A | 2005-11-10 |
Foreign References:
| WO2002000216A1 | 2002-01-03 | |||
| WO2003092622A2 | 2003-11-13 | |||
| WO2001087837A1 | 2001-11-22 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita
Tadayuki Motoyama
Kenji Tomita