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Title:
CATECHOL-O-METHYLTRANSFERASE ACTIVATOR AND PHARMACEUTICAL COMPOSITION
Document Type and Number:
Japanese Patent JP2020055770
Kind Code:
A
Abstract:
To provide novel COMT activators, and to provide pharmaceutical compositions containing the COMT activators as an active ingredient.SOLUTION: Provided is a catechol-O-methyltransferase activator containing at least one compound selected from the group consisting of a compound represented by the following general formula (I), a stereoisomer thereof, a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable solvate thereof. In the formula, Rto Reach independently represent a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, or a hydroxy group; Rrepresents a vinyl group or a hydroxy group; and Y represents a linear or branched aliphatic hydrocarbon group having 1 to 5 carbon atoms, which may have a hydroxy group as a substituent.SELECTED DRAWING: None

Inventors:
IIJIMA HIROSHI
TAKAMIYA TOMOKO
Application Number:
JP2018186801A
Publication Date:
April 09, 2020
Filing Date:
October 01, 2018
Export Citation:
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Assignee:
UNIV NIHON
International Classes:
A61K31/047; A61K31/045; A61K31/19; A61K31/215; A61K31/352; A61K31/365; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P13/12; A61P43/00
Attorney, Agent or Firm:
Nishizawa Kazumi
Junichi Kobayashi
Igarashi Mitsunaga