カテプシンシステインプロテアーゼ阻害薬

Japanese Patent JP2004531486

A

This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.

Prasit, Petsupibun
Bailey, Christopher Ian
Robixyo, Jjoel Stephanu
Brack, Dobrieu Cameron
Setu Tei, Ed Waldo El
Rizebski, Robert M
Palmer, James Tay

JP2002569079A

October 14, 2004

March 01, 2002

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Merck Frost Canada and Company

A61K31/275; A61K31/341; A61K31/381; A61K31/401; A61K31/41; A61K31/4196; A61K31/445; A61K31/495; A61K31/496; A61K31/506; A61K45/00; A61P1/02; A61P19/02; A61P19/08; A61P19/10; A61P29/00; A61P35/00; A61P43/00; C07C255/29; C07C323/60; C07C323/61; C07C323/62; C07D207/16; C07D209/18; C07D209/42; C07D211/20; C07D211/58; C07D211/60; C07D215/12; C07D231/12; C07D231/18; C07D231/38; C07D231/40; C07D233/54; C07D239/42; C07D249/12; C07D257/04; C07D257/06; C07D261/14; C07D271/08; C07D275/02; C07D275/03; C07D285/06; C07D295/08; C07D295/096; C07D295/12; C07D295/135; C07D295/155; C07D295/205; C07D307/22; C07D307/66; C07D333/28; C07D333/36; C07D333/54; C07D401/04; C07D409/10; C07D417/04; C07D417/10; C07D487/08; (IPC1-7): C07C323/60; A61K31/275; A61K31/341; A61K31/381; A61K31/401; A61K31/41; A61K31/4196; A61K31/445; A61K31/495; A61K31/496; A61K31/506; A61K45/00; A61P1/02; A61P19/02; A61P19/08; A61P19/10; A61P29/00; A61P35/00; C07D209/18; C07D211/60; C07D231/40; C07D239/42; C07D249/12; C07D257/04; C07D261/14; C07D271/08; C07D275/02; C07D295/08; C07D295/12; C07D307/22; C07D333/36

Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura

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