Title:
カテーテル・ロッキング溶液およびカテーテル・ロッキング療法
Document Type and Number:
Japanese Patent JP6909226
Kind Code:
B2
Abstract:
Various embodiments relate to catheter locking solutions and catheter locking therapies with use of trisodium citrate and ethyl alcohol, and in particular 4.0 to 15.0 weight/volume % trisodium citrate as an anticoagulant component and/or an antibacterial component and 15.0 to 25.0 volume/volume % ethyl alcohol as an antibacterial component. Use of the catheter locking solution and catheter locking therapy can reduce treatment failure during medical procedures that may employ catheters to supply treatment by at least significantly reducing the risks associated with bloodstream infections, catheter system malfunction, emboli formation, patient discomfort, and patient illness. These benefits can be partially due to the synergistic antibacterial effects of the trisodium citrate and ethyl alcohol in solution, generating an effective catheter locking solution with minimal concentrations of ethyl alcohol.
Inventors:
Prem Kumar Bab
Benjamin Earl Brozanski
Lisa Pagano
Jeffrey S. Bennett
Benjamin Earl Brozanski
Lisa Pagano
Jeffrey S. Bennett
Application Number:
JP2018541328A
Publication Date:
July 28, 2021
Filing Date:
February 06, 2017
Export Citation:
Assignee:
Medical Components, Incorporated
International Classes:
A61L29/16; A61K9/08; A61K47/10; A61K47/12; A61L33/04
Domestic Patent References:
| JP2004516041A | ||||
| JP2002523336A | ||||
| JP2015525801A | ||||
| JP2002336362A |
Foreign References:
| US20080279907 | ||||
| KR1020070114737A |
Other References:
A.L. Bell et.al.,Ethanol/Trisodium citrate for hemodialysis catheter lock,Clinical Nephrology,ドイツ,Dustri-Verlag Dr. K. Feistle,2004年,62,369-373
Attorney, Agent or Firm:
Michiko Matsutani
Haruhiko Ema
Haruhiko Ema