Title:
組織特異的送達用のカチオン性脂質組成物
Document Type and Number:
Japanese Patent JP7379325
Kind Code:
B2
Abstract:
Provided herein are, inter alia, compositions and methods useful for the in vivo delivery of bioactive agents (e.g., therapeutic or diagnostic agents). The compositions provided herein include cationic lipids, helper lipids and a biostability enhancing agent, which together form a lipid aggregate with the bioactive agent and allow for the systemic delivery of the bioactive agent to, for example, lung tissue without the requirement for biomolecular targeting.
Inventors:
Mishra Shikha
Domorera du Jugsavier
Domorera du Jugsavier
Application Number:
JP2020512589A
Publication Date:
November 14, 2023
Filing Date:
July 17, 2018
Export Citation:
Assignee:
Life Technologies Corporation
International Classes:
A61K47/18; A61K31/7105; A61K47/24; A61K47/28; A61K47/34; A61P11/00; A61P11/06; A61P35/00; C12N5/071; C12N5/10; C12N15/09; C12N15/11; C12N15/113
Foreign References:
| WO2016011203A1 | ||||
| WO2016206626A1 | ||||
| WO2000027795A1 | ||||
| WO2012068176A1 | ||||
| WO2011076807A2 |
Other References:
HARVIE P; ET AL,JOURNAL OF PHARMACEUTICAL SCIENCES,米国,2000年05月,VOL:89, NR:5,PAGE(S):652 - 663,http://dx.doi.org/10.1002/(SICI)1520-6017(200005)89:5<652::AID-JPS11>3.0.CO;2-H
KOZUE ABE; ET AL,COLLOIDS AND SURFACES A: PHYSIOCHEMICAL AND ENGINEERING ASPECTS,NL,2015年06月,VOL:474,PAGE(S):63 - 70,http://dx.doi.org/10.1016/j.colsurfa.2015.03.006
KOZUE ABE; ET AL,COLLOIDS AND SURFACES A: PHYSIOCHEMICAL AND ENGINEERING ASPECTS,NL,2015年06月,VOL:474,PAGE(S):63 - 70,http://dx.doi.org/10.1016/j.colsurfa.2015.03.006
Attorney, Agent or Firm:
Shinichiro Tanaka
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Nanae Matsuda
Takamitsu Hoshino
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Nanae Matsuda
Takamitsu Hoshino