Title:
CD200 INHIBITORS AND METHODS OF USE THEREOF
Document Type and Number:
Japanese Patent JP2021120405
Kind Code:
A
Abstract:
To provide CD200 inhibitors and methods of use thereof.SOLUTION: The present invention provides in certain embodiments compositions comprising at least one CD200 inhibitor, and methods of reversing or modulating immune suppression in a patient having a disease or disorder arising from abnormal cell growth, functionality or behavior, the methods comprising administering to a patient in need thereof a CD200 inhibitor composition. The present invention provides a composition comprising at least one CD200 inhibitor. In certain embodiments, the composition further comprises a cancer vaccine. In certain embodiments, the cancer vaccine is a tumor lysate. In certain embodiments, the tumor lysate is substantially devoid of CD200.SELECTED DRAWING: Figure 1
Inventors:
MICHAEL OLIN
Application Number:
JP2021083194A
Publication Date:
August 19, 2021
Filing Date:
May 17, 2021
Export Citation:
Assignee:
UNIV MINNESOTA
International Classes:
A61K45/00; A61K9/08; A61K38/08; A61K38/10; A61K38/16; A61K38/20; A61K39/00; A61K39/39; A61K39/395; A61K45/06; A61K47/64; A61P35/00; C07K7/06; C07K7/08; C12N15/12; C12N15/86; C12N15/861
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita