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Title:
核の機械的シグネチャに基づく細胞分類
Document Type and Number:
Japanese Patent JP7148530
Kind Code:
B2
Abstract:
The present invention relates to a method and system for identifying mechanical properties of a cell nucleus through a label-free cell analysis based on Brillouin light scattering techniques. The present application additionally provides a method and system for identifying cancerous cells based on mechanical properties of the cell nucleus.

Inventors:
Scarseri, Giuliano
Zan, Zitao
Kim, hanyup
Application Number:
JP2019547270A
Publication Date:
October 05, 2022
Filing Date:
March 01, 2018
Export Citation:
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Assignee:
University of Maryland, College Park
International Classes:
G01N21/47
Domestic Patent References:
JP2008039635A
JP61260144A
Foreign References:
WO2007034802A1
US20120129189
Other References:
ZHANG et al.,Brillouin flow cytometry for label-free mechanical phenotyping of the nucleus,Lab Chip,2017年02月14日,Vol.17/Iss.4,PP.663-670
ZHANG et al.,Line-scanning Brillouin microscopy for rapid non-invasive mechanical imaging,SCIENTIFIC REPORTS,2016年10月14日,Vol.6/No.35398,PP.1-7
ANTONACCI et al.,Biomechanics of subcellular structures by non-invasive Brillouin microscopy,SCIENTIFIC REPORTS,2016年11月15日,Vol.6/No.37217,PP.1-6
Attorney, Agent or Firm:
Okabe
Masami Saito
Usui Shinichi