Title:
インターロイキン－１活性の阻害剤としての化学化合物
Document Type and Number:
Japanese Patent JP7163293
Kind Code:
B2
Abstract:
The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.
Inventors:
Stafford, Jeffrey A.
Veale, James M.
Torzos, Rinny Lynn
McBride, Christopher
Veale, James M.
Torzos, Rinny Lynn
McBride, Christopher
Application Number:
JP2019539814A
Publication Date:
October 31, 2022
Filing Date:
January 22, 2018
Export Citation:
Assignee:
Genentech, Incorporated
International Classes:
C07D471/04; A61K31/437; A61K31/4985; A61K31/5365; A61K31/537; A61K31/553; A61P1/00; A61P1/16; A61P3/04; A61P3/10; A61P5/00; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P19/06; A61P25/00; A61P25/14; A61P25/16; A61P25/24; A61P25/28; A61P29/00; A61P31/12; A61P33/06; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P37/06; A61P43/00; C07D487/04; C07D498/04; C07D498/20
Foreign References:
| WO2013031931A1 | ||||
| WO2016131098A1 | ||||
| WO2019043610A1 |
Other References:
ASANO, Toru,J.Med.Chem.,2012年,55,7772-7785
Attorney, Agent or Firm:
Sonoda & Kobayashi Patent Attorneys Corporation
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