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Title:
CHEMICAL PROCESS FOR PREPARING PYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF
Document Type and Number:
Japanese Patent JP2019196359
Kind Code:
A
Abstract:
To provide a method for producing intermediates for preparing ceritinib.SOLUTION: There is provided a method for preparing (C2-1), comprising reacting (A) with (B) in a solvent in the presence of at least one catalyst, wherein P is a protecting group and T and X1 can be independently C1 and the like.SELECTED DRAWING: None

Inventors:
TOBIAS KAPFERER
GONG BAOQING
MARC CLINTON DAVIS
ZHENG XUCHUN
HAR DENIS
Application Number:
JP2019111950A
Publication Date:
November 14, 2019
Filing Date:
June 17, 2019
Export Citation:
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Assignee:
NOVARTIS AG
International Classes:
C07D211/28; C07D213/30; C07D239/42; C07D239/48
Domestic Patent References:
JP2013545812A2013-12-26
Foreign References:
CN104356050A2015-02-18
CN104356112A2015-02-18
CN103992262A2014-08-20
CN104109149A2014-10-22
Other References:
J. ORG. CHEM., vol. 42, no. 10, JPN6020024863, 1977, pages 1821 - 1823, ISSN: 0004467049
社団法人日本化学会, 第5版 実験化学講座13 有機化合物の合成I−炭化水素・ハロゲン化物−, JPN6020024865, 2004, pages 102 - 104, ISSN: 0004467050
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Ryo Hoshikawa
Yasuhito Suzuki