化学的にプログラム可能な免疫 - Alter Themune Technologliers, LRC

Title:

化学的にプログラム可能な免疫

Document Type and Number:

Japanese Patent JP2012526130

Kind Code:

A

Abstract:

Methods and compositions for immediately immunizing an individual against any molecule or compound are provided. The present invention is directed to an immunity linker with at least two sites; (1) at least one first binding site that binds to an immune response component in an individual, and (2) at least one second binding site that binds specifically to a desired compound or molecule, the target. The second binding sites are preferably thiolated aptamers that have the benefit of increased stability, resistance to degradation and longer circulating half life. Methods of making and using pharmaceutical compositions including immunity linker molecules having a thiolated aptamer are also provided.

More Like This:

WO/2017/096276	ANTI-GITR ANTIBODIES AND METHODS OF USE THEREOF
WO/2013/036303	INDUCED TOLEROGENIC DENDRITIC CELLS TO REDUCE SYSTEMIC INFLAMMATORY CYTOKINES
WO/2017/053918	CROSS-REACTIVE T-CELL EPITOPES OF HIV, SIV, AND FIV FOR VACCINES IN HUMANS AND CATS

Inventors:

Caribe Mullis
Jebal Atha Bibe Cananda
Joffnathan Rloyd Kiel
Ronald M. Kuoku

Application Number:

JP2012509945A

Publication Date:

October 25, 2012

Filing Date:

May 05, 2010

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Alter Themune Technologliers, LRC

International Classes:

A61K39/00; A61P31/04; A61P31/16; C12N15/115

Attorney, Agent or Firm:

Toru Ishikawa

Previous Patent: 脂肪酸代謝および貯蔵を画像化するためのＰＥＴ放射性追跡子

Next Patent: ピラゾロピリジン