Title:
ケモカイン受容体のジアゼパン誘導体モジュレーター
Document Type and Number:
Japanese Patent JP5016666
Kind Code:
B2
Abstract:
The invention is concerned with novel diazepan derivatives of formula (I) wherein A, X, R3, R4, R5, R6, R8, R9, R10, R11, R12, R13, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.
Inventors:
Shrimp, Johannes
Green,rook
Matthew, Patrizio
Ricklin, Fabian
Roche, Olivier
Zam, peter
Green,rook
Matthew, Patrizio
Ricklin, Fabian
Roche, Olivier
Zam, peter
Application Number:
JP2009505847A
Publication Date:
September 05, 2012
Filing Date:
April 11, 2007
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D243/08; A61K31/551; A61P1/04; A61P3/10; A61P7/02; A61P9/00; A61P9/04; A61P9/08; A61P9/10; A61P9/14; A61P11/06; A61P13/12; A61P17/02; A61P19/02; A61P25/00; A61P25/04; A61P29/00; A61P37/06; A61P43/00; C07D401/06; C07D401/14; C07D403/06; C07D403/12; C07D405/06; C07D405/12; C07D471/10; C07D498/10
Foreign References:
| WO2004092124A1 | ||||
| WO2004094371A1 | ||||
| WO2004084898A1 |
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito