クロマトグラフィー材料及びその調製方法

Japanese Patent JP6490208

B2

A chromatographic material comprising a zwitterionic ligand covalently bound to a substrate, the ligand preferably has a formula II: wherein R1, R2, R3 are independently selected from an oxygen atom that is configured to connect to a substrate atom in the substrate, an oxygen atom that is configured to connect to a silicon atom of an adjacent ligand, a hydroxyl group, a halogen atom, an alkoxy group, a dialkylamino group, an acyl group, an alkyl group, or an aryl group; L1, L2 and L3 are independently hydrophobic moieties; each containing 2 to 30 carbon atoms, wherein there are at least 10 carbon atoms in the combined chain lengths of L1, L2 and L3; X is an O atom, S atom, amide group or sulfonamide group; n is 0 or 1; R4, R5 are independently selected from a hydrogen atom or a hydrocarbon moiety containing 1 to 20 carbon atoms; and Rf is a negatively charged moiety comprising a sulfonic, carboxylic, or phosphonic functional group.

Liu Xiao Dong
Williams richard tee
Tui Xiao

JP2017522014A

March 27, 2019

October 16, 2015

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Thermo Electron Manufacturing Limited
Dionex Corporation

B01D15/36; B01D15/32; B01J20/22; B01J20/281; B01J20/286; B01J20/30; C01B33/18; G01N30/02

JP6229994A
JP2011523041A
JP2005187456A
JP2010071707A

EP2210662A1
US20090202816
US20060054559
WO2006088760A1
US6884345

BOGUSLAW BUSZEWSKI,HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY (HILIC)-A POWERFUL SEPARATION TECHNIQUE,ANALYTICAL AND BIOANALYTICAL CHEMISTRY,ドイツ,SPRINGER,2011年 8月31日,VOL:402, NR:1,,PAGE(S):231 - 247,URL,http://dx.doi.org/10.1007/s00216-011-5308-5

Shinichiro Tanaka
Disciple Maru Ken
▲吉▼田 和彦
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Shimura

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