Title:
安息香酸リチウムの共結晶及びその使用
Document Type and Number:
Japanese Patent JP6958923
Kind Code:
B2
Abstract:
The present disclosure provides co-crystals of a lithium benzoate compound and a co-former compound of Formula (I)Also provided herein are methods of preparing the co-crystals and uses thereof in treating and/or reducing the risk for neuropsychiatric disorder (e.g., schizophrenia, psychotic disorders, depressive disorders, bipolar disorders, or neurogenerative disorders).
Inventors:
Quochoan Emil Tsai
One Ching-Chung
Shay Tien-Run
Lo Yuan-Chun
One Ching-Chung
Shay Tien-Run
Lo Yuan-Chun
Application Number:
JP2018564930A
Publication Date:
November 02, 2021
Filing Date:
June 13, 2017
Export Citation:
Assignee:
Sinews International (Taiwan) Corporation
International Classes:
C07C63/08; A61K31/192; A61P3/06; A61P3/08; A61P3/10; A61P9/12; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/30; C07C57/10; C07C57/44; C07D213/80
Domestic Patent References:
| JP2014508814A | ||||
| JP2014502251A | ||||
| JP6502184A | ||||
| JP2010106001A | ||||
| JP2011518131A |
Foreign References:
| WO2014172650A1 | ||||
| US20130102781 | ||||
| WO2010005581A1 | ||||
| WO2015147742A1 | ||||
| CA2505808A1 | ||||
| WO2016081365A1 | ||||
| WO2015086843A2 |
Other References:
Butterhof, Christian et al.,Influence of Cation Size on the Co-crystallisation of Benzoic Acid with Different Benzoates,Zeitschrift fuer Anorganische und Allgemeine Chemie,2013年,Vol.639(2),p.308-311
Lombardo, Giuseppe M. et al.,Functional hybrid co-crystals of humic substances: a growth forecast,CrystEngComm,2014年,Vol.16(26),p.5917-5923, S1-S11
Smith, Adam J. et al.,Improving Lithium Therapeutics by Crystal Engineering of Novel Ionic Cocrystals,Molecular Pharmaceutics ,2013年,Vol.10(12),p.4728-4738
Bak, Annette et al.,The co-crystal approach to improve the exposure of a water-insoluble compound: AMG 517 sorbic acid co-crystal characterization and pharmacokinetics,Journal of Pharmaceutical Sciences,2008年,Vol.97(9),p.3942-3956
Lombardo, Giuseppe M. et al.,Functional hybrid co-crystals of humic substances: a growth forecast,CrystEngComm,2014年,Vol.16(26),p.5917-5923, S1-S11
Smith, Adam J. et al.,Improving Lithium Therapeutics by Crystal Engineering of Novel Ionic Cocrystals,Molecular Pharmaceutics ,2013年,Vol.10(12),p.4728-4738
Bak, Annette et al.,The co-crystal approach to improve the exposure of a water-insoluble compound: AMG 517 sorbic acid co-crystal characterization and pharmacokinetics,Journal of Pharmaceutical Sciences,2008年,Vol.97(9),p.3942-3956
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei