Title:
制御されたドラッグデリバリーの方法としてのコドラッグ
Document Type and Number:
Japanese Patent JP4039683
Kind Code:
B2
Abstract:
A codrug composition of at least two drug compounds covalently linked to one another via a labile bond to form a single codrug composition, and methods of use of the codrug for the treatment of various medical conditions. The codrug may be administered by itself or in the form of a bioerodible or nonbioerodible substance.
Inventors:
Ashton, Paul
Crooks, peter, anthony
Riggs, robert, mac
Shinkowski, Thaddeus
Shinkowski, Grazina
Crooks, peter, anthony
Riggs, robert, mac
Shinkowski, Thaddeus
Shinkowski, Grazina
Application Number:
JP52002395A
Publication Date:
January 30, 2008
Filing Date:
February 17, 1994
Export Citation:
Assignee:
University of Kentucky Research Foundation
International Classes:
A61K9/00; A61K31/19; A61K45/00; A61K31/505; A61K31/513; A61K31/52; A61K31/557; A61K31/57; A61K47/48; A61P27/02; A61P27/12; A61P43/00; C07C57/58; C07D239/553; C07D285/10; C07D285/135; C07D473/00; C07J1/00; C07J5/00; C07J21/00; C07J43/00; C07J71/00; C07D239/54; C07D285/12
Domestic Patent References:
| JP4264089A | ||||
| JP3505586A |
Foreign References:
| US5157151 |
Other References:
J.Med.Chem.,Vol.33,No.1,p.77-86,1990年
J.Med.Chem,Vol.29,No.1,p.84-89,1986年
J.Med.Chem,Vol.35,No.14,p.2711-2712,1992年
Anti-Cancer Drug Design,Vol.1,No.2,p.133-140,1986年
Journal of Pharmaceutical Sciences,Vol.73,No.2,p.278-280,1984年
J.Med.Chem,Vol.29,No.1,p.84-89,1986年
J.Med.Chem,Vol.35,No.14,p.2711-2712,1992年
Anti-Cancer Drug Design,Vol.1,No.2,p.133-140,1986年
Journal of Pharmaceutical Sciences,Vol.73,No.2,p.278-280,1984年
Attorney, Agent or Firm:
Yoshiki Hasegawa
Shiro Terasaki
Yuichi Yamada
Shiro Terasaki
Yuichi Yamada