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Title:
癌治療のためDNAワクチンと生物学的修飾因子の併用
Document Type and Number:
Japanese Patent JP4354826
Kind Code:
B2
Abstract:
The present disclosure relates to the combination of a DNA vaccination strategy that makes use of a nucleic acid encoding an immunogenic polypeptide, with a non- immunosuppressive inducer of tumor cell differentiation and/or apoptosis or a tumor cell modifier, useful for cancer therapy. Vaccine compositions and kits are provided, as well as specific nucleic acid constructs that are particularly suitable for the preparation of such compositions.

Inventors:
Padua, Rose Ann
Chominnes, Christine
Sharon, Dominique
Application Number:
JP2003587410A
Publication Date:
October 28, 2009
Filing Date:
April 24, 2003
Export Citation:
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Assignee:
Institut Nacional de la Santoue de la Leche Che Medical (ENS A/M)
International Classes:
C12N15/09; A61J1/05; A61K31/164; A61K31/203; A61K31/7088; A61K33/24; A61K38/00; A61K38/16; A61K39/00; A61K39/39; A61K45/00; A61K45/06; A61K48/00; A61P35/00; A61P35/02; C07K16/30
Domestic Patent References:
JP2001522799A
Other References:
PNAS,Vol.94(1997)p.2551-2556
STEVENSON F K,ANNALS OF ONCOLOGY,NL,KLUWER,1999年12月,V10 N12,P1413-1418
CATHERINE A KING,NATURE MEDICINE,米国,NATURE PUBLISHING,1998年11月,V4 N11,P1281-1286
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei
Masaya Nishiyama