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Title:
抗エンドグリン抗体及び抗VEGF剤を用いる癌の併用療法
Document Type and Number:
Japanese Patent JP5829260
Kind Code:
B2
Abstract:
The present application relates to compositions of chimeric anti-endoglin antibodies and anti-VEGF agents. Another aspect relates to the use of chimeric anti-endoglin antibodies and Bevacizumab. Another aspect relates to the use of the compositions to inhibit VEGF induced sprouting. Another aspect relates to the use of the compositions to inhibit angiogenesis.

Inventors:
Sure, Charles, Pee.
Ben Kay Son
Application Number:
JP2013257598A
Publication Date:
December 09, 2015
Filing Date:
December 13, 2013
Export Citation:
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Assignee:
Tracon Pharmaceuticals, Inc.
International Classes:
A61K39/395; A61K45/00; A61P1/04; A61P19/02; A61P27/02; A61P27/12; A61P29/00; A61P35/00; A61P35/04; A61P43/00
Foreign References:
US5928641
WO2009033581A1
WO2008038127A1
Other References:
Journal of Clinical Oncology,2009 ASCO Annual Meeting Proceedings(Post-Meeting Edition).,2009年 5月20日,Vol.27,No.15S,3518
Cancer Immunol Immunother,2006年,Vol.55,p.140-150
Attorney, Agent or Firm:
Asamura patent office