Title:
TNFおよびα-ガラクトシルセラミドを使用する併用療法
Document Type and Number:
Japanese Patent JP2010519274
Kind Code:
A
Abstract:
The invention relates to the treatment of cancer. More specifically the invention shows that the anti-cancer activity in mammals can be augmented by administering to the mammalian host a combination of a synergistically effective amount of TNF and alfa-galactosylceramide.
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Inventors:
Blocker, Peter
Elevato, Dirk
Hugue, Leander
Elevato, Dirk
Hugue, Leander
Application Number:
JP2009550701A
Publication Date:
June 03, 2010
Filing Date:
February 20, 2008
Export Citation:
Assignee:
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW(VIB VZW)
Universiteit Gent
Universiteit Gent
International Classes:
A61K38/00; A61K31/7028; A61K45/00; A61P35/00; A61P43/00
Other References:
JPN6012054914; Ｅｕｒ．Ｊ．Ｂｉｏｃｈｅｍ．， １９８５， Ｖｏｌ． １５２， Ｎｏ． ３， Ｐ． ５１５-５２２
JPN6012054918; Ｃｌｉｎ．Ｅｘｐ．Ｍｅｔａｓｔａｓｉｓ， ２０００， Ｖｏｌ． １８， Ｎｏ． ２， Ｐ． １４７-１５３
JPN6012054920; Ｃａｎｃｅｒ Ｓｃｉ．， ２００８．Ｊａｎ．， Ｖｏｌ． ９９， Ｎｏ． １， Ｐ． １１３-１２０
JPN6012054918; Ｃｌｉｎ．Ｅｘｐ．Ｍｅｔａｓｔａｓｉｓ， ２０００， Ｖｏｌ． １８， Ｎｏ． ２， Ｐ． １４７-１５３
JPN6012054920; Ｃａｎｃｅｒ Ｓｃｉ．， ２００８．Ｊａｎ．， Ｖｏｌ． ９９， Ｎｏ． １， Ｐ． １１３-１２０
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito