Title:
血管作用剤の組合せ物、それらの薬剤および化粧品分野での使用、ならびにそれらを含む製剤
Document Type and Number:
Japanese Patent JP4964590
Kind Code:
B2
Abstract:
This invention relates to combinations of vasoactive substances which act at venous or arterial level with phosphodiesterase inhibitors including phosphodiesterase V, in particular:
- esculoside;
- at least one compound selected from icarin or derivatives thereof or extracts containing it, Gingko biloba dimeric flavones either in the free form or complexed with phospholipids, amentoflavone;
- at least one compound selected from escin, escin beta-sitosterol complexed with phospholipids, sericoside, sericoside complexed with phospholipids or Centella asiatica extract in the free form or complexed with phospholipids. The formulations according to the invention are useful in reducing panniculopathy and problems associated with venous insufficiency of the lower limbs.
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Inventors:
Bombardelli, Ezio
Application Number:
JP2006518124A
Publication Date:
July 04, 2012
Filing Date:
July 06, 2004
Export Citation:
Assignee:
Indena Esse Pia
International Classes:
A61K8/49; A61K8/60; A61K8/97; A61K31/352; A61K31/37; A61K31/70; A61K31/7024; A61K31/704; A61K31/7048; A61K36/16; A61K36/23; A61K38/00; A61P9/00; A61P17/00; A61P43/00; A61Q19/00; A61Q19/06
Domestic Patent References:
JP3145427A | ||||
JP8059463A | ||||
JP8169896A | ||||
JP3167133A | ||||
JP63277691A | ||||
JP2003502376A | ||||
JP2004532273A |
Foreign References:
WO2002098436A1 |
Attorney, Agent or Firm:
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Ishibashi Masayuki
Masaaki Ogata