Title:
造影用の複合粒子、複合粒子の製造方法、細胞、細胞構造体および混合分散液
Document Type and Number:
Japanese Patent JP7241355
Kind Code:
B2
Abstract:
The purpose of the present invention is to provide composite particles for imaging that have high biodegradability after imaging. To achieve the above purpose, the composite particles for imaging according to the present invention are configured such that the ratio (long-term residual amount/short-term residual amount) of a long-term residual amount, which is the average value of the contrast rate after six days in a cell and the contrast rate after 11 days in a cell of the same type, and a short-term residual amount, which is the contrast rate after two days in a cell of the same type, is less than 99%.
Inventors:
Chie Inui
Yasuhiko Tabata
Akihiro Maesawa
Mochizuki Makoto
Natsumi Hirayama
Yasuhiko Tabata
Akihiro Maesawa
Mochizuki Makoto
Natsumi Hirayama
Application Number:
JP2019551100A
Publication Date:
March 17, 2023
Filing Date:
October 19, 2018
Export Citation:
Assignee:
Konica Minolta Co., Ltd.
Yasuhiko Tabata
Yasuhiko Tabata
International Classes:
A61K49/14; A61K9/14; A61K9/48; A61K47/02; A61K47/42; A61K49/08; C12N5/071
Domestic Patent References:
| JP2002517085A | ||||
| JP2008150596A | ||||
| JP2010540513A | ||||
| JP2009519894A | ||||
| JP2009536151A |
Other References:
TOMITAKA, Asahi et al.,Preparation of biodegradable iron oxide nano-particles with gelatin for magnetic resonance imaging,Inflammation and Regeneration,2014年,Vol.34, No.1,pp.45-55,ISSN:1880-9693, 特に第46頁右欄第8行~第47頁第29行、第49頁右欄第9行~第12行、第51頁左欄
GUPTA, Ajay Kumar et al.,Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications,Biomaterials,2005年,Vol.26,pp.3995-4021,ISSN:0142-9612
GUPTA, Ajay Kumar et al.,Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications,Biomaterials,2005年,Vol.26,pp.3995-4021,ISSN:0142-9612
Attorney, Agent or Firm:
Patent Attorney Corporation Washida International Patent Office
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